Pamlico BioPharma has existing collaborations with leading research institutions and companies that support various aspects of our company’s research and development activities.
OMRF Core Antibody Lab
The Human Core Antibody Lab at the Oklahoma Medical Research Foundation (OMRF) is one of the few laboratories in the world that produces fully-human, full-length, antigen-specific antibodies for use in studying human immune responses. The Core has achieved breakthroughs in antibody technology and has produced hundreds of high affinity protective antibodies to influenza, anthrax lethal toxin, and various S. pneumoniae polysaccharides under partnership with Pamlico BioPharma.
Judith James, M.D., Ph.D.
Dr. James is a Professor of Medicine, Adjunct Professor of Pathology, Adjunct Professor of Microbiology and Immunology and George Lynn Cross Research Professor at the University of Oklahoma Health Sciences Center. She also serves as the Chair of the Arthritis and Clinical Immunology Program and holds the Lou Kerr Chair in Biomedical Research at OMRF. She currently serves as the principal investigator for an NIH-funded Autoimmunity Center of Excellence, Rheumatic Disease Research Cores Center, and Center of Biomedical Research Excellence. Dr. James has received several awards including the Presidential Early Career Award for Scientists. Dr. James serves in national/international leadership positions with the American College of Rheumatology and the Lupus Foundation of America. She is a standing study section member with the National Institutes of Health. Dr. James currently serves as a national Councilor for the National Institutes of Arthritis, Musculoskeletal and Skin Disease.
Kenneth Smith, Ph.D.
Dr. Smith is the Director of the Human Core Antibody Lab and Assistant Research Member at OMRF, a leading research scientist in the development of antigen-specific antibodies for use in researching human immune responses. Under Dr. Smith, the OMRF Human Antibody Core Facility has produced and characterized over 600 fully human, full-length monoclonal antibodies to a variety of antigens including influenza (seasonal H1N1, swine origin H1N1, H3N2 and both B lineages), Streptococcus pneumoniae polysaccharides (24 serotypes and cell wall polysaccharides), varicella zoster, and anthrax protective antigen.
Cytovance® Biologics is a biopharmaceutical contract manufacturing company specializing in the production of therapeutic proteins and antibodies from both mammalian cell culture and microbial fermentation. In addition to its cGMP manufacturing services, the company offers process development, cGMP cell banking and support services from its Oklahoma City state-of-the-art facilities. Pamlico recently partnered with Cytovance in support of our lead program in pneumococcal pneumonia for GMP manufacturing to support IND directed activities and clinical trial material antibody manufacturing.
Diagnostics Consulting Network is a globally-recognized leader for contract development and commercialization of high performance rapid assay systems. DCN focuses on lateral flow, flow-through, and microfluidic assay formats. Their experience includes qualitative, quantitative, visual or reader-based, and single- or multi-plexed assay systems. Pamlico BioPharma and DCN have partnered to develop the first serotype-specific S. pneumoniae lateral-flow diagnostic assay as a companion, point-of-care diagnostic tool.